The emergence of personalized medicine is having a significant impact on the process of developing new therapeutics and associated diagnostics. The basic process of discovery and development is shown in the figure below. Both pipelines begin with an understanding of the molecular causes and effects of disease, discovery and validation of markers, and identification of targets. While therapeutics can be developed independently of diagnostics, the advent of personalized medicine is leading to development of therapeutics and diagnostics in an interdependent, collaborative manner.